Can hormone replacement therapy increase risk of endometrial cancer?
Endometrial cancer happens when cancerous cells grow and spread in the endometrium, or the inside lining of the uterus. Women who are going through menopause, are obese, or have never been pregnant are all at risk of endometrial cancer. Additionally, women who are undergoing hormone replacement therapy (HRT) to fight against symptoms of menopause are considered more prone to this disease.
One factor that could increase your risk of endometrial cancer is the shift in the balance of two female hormones, progesterone and estrogen. The American Cancer Society stated that taking estrogen without progesterone during HRT increases a woman’s risk of endometrial cancer. As such, it is important to ask your doctor about your endometrial cancer risk before undergoing any type of HRT.
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